Intermediate of Entecavir 1
(1s-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol
CAS: 188399-48-6;110567-21-0
Molecular Formula: C13H16O2
Intermediate of Entecavir 1 - Names and Identifiers
Intermediate of Entecavir 1 - Physico-chemical Properties
| Molecular Formula | C13H16O2 |
| Molar Mass | 204.26 |
| Density | 1.112 |
| Boling Point | 319 ºC |
| Flash Point | 135 ºC |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Light Yellow Oil with White Particulates |
| pKa | 14.65±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.565 |
Intermediate of Entecavir 1 - Introduction
(1S-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Molecular formula: C11H16O2
-Molecular weight: 180.24g/mol
-Melting point:-50 ° C
-Boiling point: 232-233 ° C
-Solubility: Soluble in ethanol, ether and other organic solvents, insoluble in water
Use:
(1s-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol has a wide range of applications in the field of organic synthesis. It is often used as an intermediate for the synthesis of complex organic compounds such as different types of natural products, pharmaceuticals and pesticides.
Method:
(1S-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol can be prepared in many ways, one of which is commonly used by hydroxymethylation of cyclopentene, the resulting product is then subjected to chiral selective reduction.
Safety Information:
(1s-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol is generally relatively safe when used and stored correctly. However, use caution and observe the following safety measures:
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-use to maintain a good ventilation environment, avoid inhalation of its vapor.
-Avoid contact with strong oxidants and high temperatures to prevent fire or explosion.
-Store in a dry, cool, ventilated place, away from fire and lit items.
-Follow laboratory safety regulations during use and wear appropriate protective equipment such as goggles, gloves and laboratory coats.
Nature:
-Appearance: colorless liquid
-Molecular formula: C11H16O2
-Molecular weight: 180.24g/mol
-Melting point:-50 ° C
-Boiling point: 232-233 ° C
-Solubility: Soluble in ethanol, ether and other organic solvents, insoluble in water
Use:
(1s-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol has a wide range of applications in the field of organic synthesis. It is often used as an intermediate for the synthesis of complex organic compounds such as different types of natural products, pharmaceuticals and pesticides.
Method:
(1S-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol can be prepared in many ways, one of which is commonly used by hydroxymethylation of cyclopentene, the resulting product is then subjected to chiral selective reduction.
Safety Information:
(1s-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol is generally relatively safe when used and stored correctly. However, use caution and observe the following safety measures:
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-use to maintain a good ventilation environment, avoid inhalation of its vapor.
-Avoid contact with strong oxidants and high temperatures to prevent fire or explosion.
-Store in a dry, cool, ventilated place, away from fire and lit items.
-Follow laboratory safety regulations during use and wear appropriate protective equipment such as goggles, gloves and laboratory coats.
Last Update：2024-04-09 02:00:43
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